Hi,
I had a similar problem with 18F4320. Using a PICSTART PLUS and MPLAB.
I bought the latest update chip for the PICSTART and that did not help. Then I contacted MICRO CHIP and was told to add a capacitor between VDD and VSS . Helped a little.
The way I got it to work is to have the 18F4320 powered up during the programming process. Using the PICSTART as an ICSP, MCLR internal, and the "ground" from the programmer connected to the pic power supply "ground".
I am not using MCLR for IO, have it set for internal to make things simple. The two programming pins are not used for IO either, again to keep things simple.
If you want to use these pins and do ICSP there are ways around it but that is another subject.
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