Did this 5 Seconds affect my TMR0 Interrupt,and I have next Time -5 Second in My Time Display!?
If you're using ON INTERRUPT, then yes. The PAUSE 5000 will definitely affect how long it will
take before your interrupt is serviced. It won't affect TMR0 counting. Only the time before
your interrupt gets serviced.

When yes what I can do to not affect My TMR0 Timer.
Use assembler interrupts. Look for Darrel Taylors' interrupt routines here.