All VSS and VDD have to be connected.
From what i see on your picture, there's few potential traces short-circuit. Assuming there's no routing mistake and the original design worked, You should do a visual inspection first then use you Multimeter.
<img SRC="http://www.picbasic.co.uk/forum/attachment.php?attachmentid=1538&stc=1&d=117673623 8">
Seems to be caused by a lack of etching time or toner transfer... i can't tell.
The overall layout and routing looks good, the final results... so so. I try to avoid 90 degree routing, the etching process work better. It have also other benefits in high frequency.
I also try to avoid unconnected 'ground plane dedicated' copper islands.
Check if there's any polarised capacitor connected backward.
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