For analog electronics, many companies offer simulator software to test and refine your hardware using their parts. Microchip has MINDI for testing op amps, comparators, and many other analog ICs. Linear Technologies and several other companies offer their versions.

A popular simulation suite that allows you to not only test hardware, but an entire PCB board -- including PIC software -- is Proteus. It'll set you back several hundred dollars, and the newest PIC chips in their library are the PIC18FxxK22; rather outdated.

The MPLABX Simulator doesn't allow you to view I/O's in real time. You have to set break points and check values in Registers at that time.

I have not heard of Virtual Breadboard so I cannot comment.