Ok, well I2C is I2C. If the chip say it will work on that protocol, then I2Cread/I2Cwrite will work.
Read the PBP manual about these 2 commands, some chips work at higher speeds and require a DEFINE to be set. This is where the datasheet for your IC will come in handy, they should say what speeds the IC work at.
If the question is chosing between these two ICs, I would use the I2C personally; simple, lots of examples in forum.
Robert




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