Hi,
If you don't really NEED the extra features of 322 and you're making, say, 100k units of your desing then those mere 10 cents per unit equals 10k in the end - 10k pure profit - simple as that.
For hobby use where you make 1 or 10 - it doesn't matter one bit, pick the one offering the greatest flexibillity. IF the design turns commercial you can always try to squeeze into a cheaper device.

Those are my thoughts....

/Henrik.