Should? maybe

Will? Only a deep dive into the datasheet can be sure of that.

PIC18F26J53 har PPS (periphial pin select or how it is spelled, menaing you can re-route HW functions to different pins)

So what PIN on the device and what PORT-id do you use?

I would not bet that all pics always gets all registers set up exactly the same everytime.. so there might be a conflict that is because of a register setting.

Before I start pulling components I would advise you to give us more details about the device setup and configuration...and PPS register settings