Yes, I've got one connected to a PIC via the UART. The PIC reads I2c sensors and returns the values to the UART. This setup allows the PICs UART to be available on my house network.
My system controls my central heating. I use a few SBL2e around the house. Only a couple are connect to a PIC. The PIC is required as the SBL2e does not connect directly to a I2C bus. I have the the other UART on the SBL2e connected to a bluetooth card allowing BT access to the central heating control, which is a router running DD-wrt linux. The other pins on the SBL2e are use to control the immersion heater and pumps and valves via 5v - 220v relays.
I found the SBL2e does just as the spec sheet says and has been total faultless for the last two years. I see they are available in the UK now at a very fair price. A great little package.
Good luck.