I keep one very old PC going because of my Protek 220 oscilloscope card. I bought the motherboard just as ISA was disappearing from new PCs. It has ISA, PCI and one AGP slot so I'm able to use newer graphics cards and monitors with it.
Even for ISA - I usually deal with Byterunner because they've proven to be very knowledgeable over the years but I assume Bert is hoping to future-proof his design and, as you said, ancient PCs wear out.
I think I'd be looking at Single Board Computers for this application.





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