Thanks for the suggestions guys. The problem is that I am going to have 8 targets. If these were all just LDRs, then it wouldn't be an issue and I could hook them up with 1k pull ups and it would be fine.

Because I need so many, I can't really use the comparators, etc of the PIC. Is there a simpler way where I can use these photodiodes on the general I/O pins?

I am also hunting around for some diodes that maybe have a narrow frequency range, so as to only respond to the laser. Then when there is no laser it would be a lot closer to 0 instead of 2 MOhms, etc.