Well, if it is truely the exact same circuit, and exact same program ...
About the only difference between a breadboard and a PCB is the extra capacitance inherent in the breadboard.
Do you have at least one 0.1uF capacitor between VDD and VSS close to the PIC?
And maybe a 10uF cap close to the USB port?
Is "Low Voltage Programming" disabled in the configs?
Is IESO disabled?
Is it the exact same crystal? Parallel or series cut?
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