This chip seems to be a nice upgrade to the more common USB-capable 18F4550. The 18F46J50 has 64 Kbytes of programming memory compared to 32 Kbytes of the 18F4550.

Also, the 18F46J50 has a very interesting feature which is "On-Chip USB Transceiver with Crystal-less operation". Which means "High-Precision Internal Oscillator (±0.15% typ.) for USB", so no need for an external crystal oscillator . I will keep this chip in mind for my own projects.

Now you have me thinking about trying the beast also

USB is something I have not played with yet. It will be interesting to see how it goes.
mackrackit,

Even a rookie like me got the USB working on a 18F4550, so you shouldn't have any problems. But, I do recommend starting with a 18F4550 chip, which is a lot easier to work with and it is well documented in this forum. The 18F46J50 chip seems to be a lot harder to make it work.

Robert